No. You need nothing else. All stock parts will work fine with 13/48.
UNLESS.......
Mostly it depends on the rear sprocket you bought.
If it's countersunk drilled for bolts or not.
The 48t I got had both countersunk holes and standard holes - so I was able to use stock Yamaha sprocket bolts to mount aftermarket sprocket.
(I did not buy renthal though....)
You'll be needing to cut chain if you got 120 links.
x-ring is fine.
No mods needed to chain guard.
I did not need any spacers or nothing.
Bolt on, cut chain to length, enjoy with big shit-eatin' grin.
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2008 WR250X
Gearing: 13t - 48t
Power Commander 5 / PC-V
Airbox Door Removed - Flapper glued - AIS removed
FmF Q4
Bridgestone Battlax BT-003rs