First thing that comes to mind is the chain skipping over sprocket teeth under acceleration.
The stock sprockets, especially the stock rear sprocket that came on 2008 model bikes, is/are most known for this because the rubber damper ring bonded to it (it's an EPA-inspired noise damper) can actually lift the chain off the sprocket a bit.
This makes chain slack adjustment more finiky when wanting to clutch 'er up for a wheelie because if it's just a little bit more loose than the recommended slack spec, you can experience this skipping you're (probably) getting.
I also feel this then encourages riders to adjust their chains too tightly, another no-no.
The quick fix is to carefully check chain slack and adjust if it's too loose according to the specification.
My personal solution is to do away with the stock sprocket, altogether, and mount a real he-man sprocket to get both a sprocket without the damper, and one that's got a few more teeth on it in order to lower the gearing to something realistic for a 250cc bike.
If you go that route, you'll need a longer chain.
Well worth it, though.