G'day all. Forgive me if this opinion is replicated from someone else - I'm at work and forum time is limited.
This is what I believe to be true - the front chain slider wears excessively if:
.Smaller sprockets than standard are used
.Chain is tight
.Rear suspension has been lowered by any means
.Soft rear suspension is chosen
Here's why. When the shock is compressed and the s/arm at its highest point, the nose of the slider is pretty much all that is being used to keep the chain from munching the s/arm. If the suspension is lowered, the upper roller is brought into play much more often ie potentially overtightening the chain and causing the lower slider nose to wear more rapidly.
I've lowered my suspension via the shock length thread, and even with a sloppy chain, slider wear is increased, and something to watch. I am heavy, and the bike is set up soft so I don't get the crap beaten out of me during long days at work. Thus the suspension is compressed often, and I've noticed the above situation now affects my bike. Pity the bloody sliders are so expensive. Pity we've got to replace them. My TTR250 has had only one new one in 74,000km. Amazing.