It's highly recommended that you get a fuel programmer if you modify the intake and exhaust.
Can you do those things without a programmer? Some have.
Should you?
I wouldn't.
I didn't.
Most don't.
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2008 WR250X
Gearing: 13t - 48t
Power Commander 5 / PC-V
Airbox Door Removed - Flapper glued - AIS removed
FmF Q4
Bridgestone Battlax BT-003rs